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目的:观察正清风痛宁缓释片联合厄贝沙坦治疗慢性肾炎蛋白尿的临床疗效。方法:将60例慢性肾炎蛋白尿患者随机分为治疗组与对照组,治疗组应用正清风痛宁缓释片联合厄贝沙坦治疗,对照组应用厄贝沙坦治疗,3个月后评价两组疗效。结果:对照组总有效率70.0%,治疗组总有效率90.2%,两组比较差异有统计学意义(P<0.05);治疗前后血尿素氮(BUN)、肌酐(Cr)、肝功能比较差异均无统计学意义(P>0.05)。结论:正清风痛宁缓释片联合厄贝沙坦是治疗慢性肾炎蛋白尿的有效方法,能明显降低24h蛋白定量,且副作用少。
Objective: To observe the clinical efficacy of Zhengqingfengtongning sustained-release tablets combined with irbesartan in the treatment of chronic nephritis proteinuria. Methods: Sixty patients with chronic nephritis proteinuria were randomly divided into treatment group and control group. The treatment group was treated with Zhengqingfengtongning sustained-release tablets combined with irbesartan. The control group was treated with irbesartan. The patients were evaluated after 3 months Two groups of curative effect. Results: The total effective rate of the control group was 70.0%, the total effective rate of the treatment group was 90.2%, the difference between the two groups was statistically significant (P <0.05); before and after treatment, the blood urea nitrogen (BUN), creatinine (Cr) No statistical significance (P> 0.05). Conclusion: Zhengqingfengtongning sustained-release tablets combined with irbesartan is an effective method for the treatment of chronic nephritis proteinuria, can significantly reduce the 24h protein quantitative, and less side effects.