着色性干皮病系遗传性疾病,多有家族史。本病作为一种易感因素,常使这类患者在紫外线作用下出现皮肤癌变。但并发眼、唇癌变者国内报道甚少,现将我院所遇一例及家系调查情况报道如下:王××,女,35岁,农民。诉约自5岁起面颊部及四肢外露部分出现点状及小片状黑色斑块,渐增多,但无何不适症状。青春期后黑斑增加较快,面部常呈暗红色,并感全身皮肤干燥、刺痒,外露部位易出现皲裂。 Scleroderma Dermatosis Department of hereditary diseases, and more family history. The disease as a susceptible factor, often make these patients appear under the action of UV skin cancer. However, complicated with eye, lip cancer patients rarely reported, now a case of our hospital and family investigation are reported as follows: Wang × ×, female, 35 years old, farmer. Appeal from the age of 5 since the cheeks and extremities revealed some punctate and small pieces of black plaque, increasing, but no symptoms. Dark spots after puberty increased rapidly, the face often dark red, and sense of dry skin, pruritus, prone to chapped parts exposed.