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目的综合分析结节性甲状腺肿合并甲状腺癌的外科手术治疗价值,为治疗结节性甲状腺肿合并甲状腺癌患者提供科学的数据参考。方法选取云浮市人民医院2013-03-2015-02收治的结节性甲状腺肿合并甲状腺癌患者临床资料45例作为研究对象,再选取同期我院收治的结节性甲状腺肿350例临床资料作为研究对象,在患者知晓情况下参与本次实验研究,采用SPSS 20.0统计学软件进行统计学分析45例结节性甲状腺肿合并甲状腺癌患者的临床治疗效果且进行1~3年随访。结果结节性甲状腺肿合并甲状腺癌中结节钙化发生例数为20例,占44.44%;结节性甲状腺肿中结节钙化发生例数为48例,占13.71%,两组钙化结节发生率数据比较差异有统计学意义,P<0.05;45例结节性甲状腺肿合并甲状腺癌患者均得到病理确诊,均实施外科手术,其中有3例行甲状腺全切除及患侧功能性颈淋巴结清除术、16例行患侧腺叶全切、峡部切除、对侧甲状腺次全切除及患侧功能性颈淋巴结清除术、18例行患侧腺叶全切、峡部切除、对侧甲状腺次全切除、8例行患侧全切除、峡部切除术。结论精确的疾病分期和复发风险评估,使甲状腺手术、淋巴结清除方式更为精准,更符合最新诊治指南的要求,可最大程度上保留腺体功能,提高甲状腺癌患者的生存质量。
Objective To analyze the value of surgical treatment of nodular goiter complicated with thyroid cancer and provide scientific data for the treatment of patients with nodular goiter complicated with thyroid cancer. Methods Forty-five patients with nodular goiter complicated with thyroid cancer who were admitted to Yunfu People’s Hospital from March 2013 to May 2015 were selected as the research object. The clinical data of 350 cases of nodular goiter admitted in our hospital were selected as the study Subjects were involved in this experimental study when patients were aware of the situation. The clinical effects of 45 patients with nodular goiter and thyroid cancer were analyzed by SPSS 20.0 statistical software and followed up for 1 to 3 years. Results The incidence of nodular calcification in nodular goiter with thyroid cancer was 20 cases (44.44%). The number of nodular calcification in nodular goiter was 48 (13.71%), and calcified nodules occurred in both groups P <0.05; 45 cases of nodular goiter with thyroid cancer patients were pathologically confirmed, were performed surgery, including 3 cases of thyroidectomy and ipsilateral functional neck lymph node dissection Sixteen patients underwent resection of ipsilateral lobectomy, isthmus resection, subtotal thyroidectomy and ipsilateral functional neck lymph node dissection, 18 cases of ipsilateral lobectomy, isthmus resection and subtotal thyroidectomy , 8 cases of ipsilateral total resection, isthmus resection. Conclusion Accurate assessment of disease staging and recurrence risk makes thyroid surgery and lymph node clearance more precise and more in line with the latest guidelines for diagnosis and treatment. It can retain gland function to the maximum extent and improve the quality of life of patients with thyroid cancer.