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目的 观察经纤维支气管镜直视下气管内肿物注射多种抗癌药,以解除支气管阻塞的疗效。方法 病人63例,男41例,女23例。年龄25~79岁。均由纤支镜活检病理诊断为肺癌,有一侧或一叶支气管阻塞。根据患者是初诊或复发,以及是否并用全身化疗来分组、用药。结果 63例中支气管通畅者30例(47.6%)、阻塞减轻27例(42.9%),总有效率90.6%。起效需注射1~3次,平均1.4次。支气管通畅需注射4~11次,平均6.3次。对于初诊患者和支气管内生长型肿瘤疗效更显著。能迅速解除因气道阻塞引起的呼吸困难,阻塞性肺炎、肺不张等。无严重并发症、病人耐受性好。结论 本方法对肺癌患者危及生命的气道阻塞是较好的姑息疗法。
Objective To observe the effect of injecting various anticancer drugs into the endotracheal mass under direct fiberoptic bronchoscopy to relieve bronchial obstruction. Methods 63 patients were male, 41 males and 23 females. Age 25 to 79 years old. All of them were diagnosed as lung cancer by pathological biopsy, with one side or one leaf bronchial obstruction. Based on whether the patient is newly diagnosed or relapsed, and whether or not to use systemic chemotherapy to group and treat. Results Among the 63 patients with bronchial patency, 30 (47.6%) had bronchial patency and 27 (42.9%) had reduced obstruction. The total effective rate was 90.6%. The onset of effect requires injection 1 to 3 times, an average of 1.4 times. Bronchial patency requires 4 to 11 injections, an average of 6.3. For the newly diagnosed patients and bronchial growth tumors more effective. Can quickly relieve dyspnea caused by airway obstruction, obstructive pneumonia, atelectasis and so on. No serious complications and good patient tolerance. Conclusion This method is a good palliative treatment for life-threatening airway obstruction in patients with lung cancer.