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女童性早熟是指女童在8岁以前出现第二性征。对性早熟患儿恰当的临床评估基于对正常青春期发育过程及引起性早熟多病因的了解。临床诊断始于详细的病史采集及全面的体格检查,在此基础上选择适当的实验室及影像学检查,根据下丘脑-垂体-性腺轴是否提前激活(促性腺激素释放激素刺激试验)来区分中枢性性早熟及外周性性早熟,对于进一步的病因鉴别诊断及治疗策略的选择均具有重要意义。
Girls precocious puberty means that girls have secondary sexual characteristics before the age of eight. The proper clinical assessment of children with precocious puberty is based on an understanding of the many causes of puberty and the development of precocious puberty. Clinical diagnosis begins with a detailed history of acquisition and a comprehensive physical examination, based on which the appropriate laboratory and imaging studies are selected to differentiate whether the hypothalamic-pituitary-gonadal axis is pre-activated (gonadotropin-releasing hormone stimulation test) Central precocious puberty and precocious puberty, for the further diagnosis of the cause of the disease and the choice of treatment strategies are of great significance.