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7岁以下儿童癫痫发病率为15∶1。成年人的癫痫发病率为200∶1。这种癲痫发作自发减少的倾向导致许多人忽视儿童年幼时期惊厥的发生。现在我们认识到已不能再证实这种预测是正确的——即惊厥本身能引起脑损伤。Minns等曾研究了惊厥导致脑损伤的发病机理.当监护各种脑疾病颅内压时,有5例儿童有惊厥其结果是出现颅内压升高。发作前正常压力为<10mmHg,在一次大惊厥后压力可增高到30～40mmHg,历时20分钟。Minns等观察到其它已知的癫痫性惊厥的作用,与颅内压改变的关系——即伴随发生的自主交感性放电。这种放电导致血压升高,心
The incidence of epilepsy in children under 7 years of age is 15: 1. The incidence of epilepsy in adults is 200: 1. The spontaneous reduction of seizures has led many to overlook the onset of convulsions in their infancy. Now we realize that this prediction can no longer be confirmed - that convulsions themselves can cause brain damage. Minns and others studied the pathogenesis of convulsions leading to brain damage.5 When monitoring intracranial pressure in various brain diseases, 5 children had seizures and the result was an increase in intracranial pressure. Normal pressure before onset of <10mmHg, after a major convulsion can increase the pressure to 30 ~ 40mmHg, which lasted 20 minutes. Minns et al. Observed the effects of other known epileptic seizures as a function of changes in intracranial pressure - the accompanying autonomic sympathetic discharge. This discharge leads to high blood pressure, heart