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目的探讨晚期先兆流产保胎患者检测宫颈分泌物的临床意义,为预测晚期先兆流产保胎结局提供依据。方法选择2012年6月—2015年12月该科收治的需住院保胎治疗的晚期先兆流产患者136例,采集患者宫颈分泌物,行支原体和沙眼衣原体检测及普通细菌培养+药敏,根据保胎结局分为保胎成功组112例和难免流产组24例,对比二组患者宫颈分泌物感染情况。结果保胎成功组支原体、沙眼衣原体及细菌阳性率分别为13.39%、1.79%、24.11%,难免流产组分别为37.50%、4.17%、41.67%,二组支原体和细菌感染率比较差异均有统计学意义(P<0.05),沙眼衣原体感染率比较差异无统计学意义(P>0.05)。结论对于晚期先兆流产保胎患者,应常规检测宫颈分泌物,并根据药敏结果及早干预,以期待改善保胎结局。
Objective To investigate the clinical significance of detecting cervical secretion in patients with advanced threatened abortion and fetus, and provide evidence for predicting the outcome of pregnancy threatened abortion. Methods From June 2012 to December 2015, 136 cases of advanced threatened abortion undergoing hospitalization for miscarriage were collected in this department. Cervical secretions, Mycoplasma and Chlamydia trachomatis tests and ordinary bacterial culture + drug sensitivity were collected. Fetal outcomes were divided into miscarriage success 112 cases and unavoidable abortion group 24 cases, compared with two groups of patients with cervical secretions infection. Results The positive rates of Mycoplasma, Chlamydia trachomatis and Bacteriosis were 13.39%, 1.79% and 24.11% respectively in the successful unhindered childbirth group and 37.50%, 4.17% and 41.67% in the unavoidable abortion group respectively. There were statistically significant differences in the infection rates of mycoplasma and bacteria among the two groups Significance (P <0.05), Chlamydia trachomatis infection rate difference was not statistically significant (P> 0.05). Conclusion For patients with advanced threatened abortion miscarriage, cervical secretions should be routinely tested and early intervention based on drug susceptibility results should be expected to improve the miscarriage outcome.