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目的:分析医院中药注射剂使用情况,为促进其临床合理使用提供参考。方法:抽取医院2015年1月~2016年1月中药注射剂处方380张,对照中药注射剂说明书,分析处方中不合理用药情况,统计不合理用药相关不良反应发生情况和涉及药品。结果:中药注射剂不合理使用处方有62张,占19.21%;不合理用药中,占前三位的为超适应证使用、超剂量或浓度使用、溶剂选择不当。中药注射剂不合理用药发生不良反应的比例为17.74%,不良反应的主要类型为皮肤及附件损害、心血管系统损害、消化系统反应、神经系统反应及全身性损害,涉及的药品包括参麦注射液、复方党参注射液、艾迪注射液、舒血宁针、丹红针、血栓通针、银杏达膜针、参芪扶正注射液。结论:基层医院中药注射剂不合理使用状况较为普遍,应加大中药注射剂使用的管理力度,提高临床医师的综合水平,严格掌握药物的用法用量和使用范围,提高临床中药注射剂用药的安全性,保证治疗安全和效果。
Objective: To analyze the use of Chinese medicine injections in hospitals and provide references for its clinical use. Methods: A total of 380 prescriptions of traditional Chinese medicine injections were collected from January 2015 to January 2016 in the hospital. The manuals were compared with those of traditional Chinese medicine injections. Analysis was made on the unreasonable use of drugs in the prescriptions. Statistics were made on the incidence of unreasonable drug-related adverse reactions and on drugs involved. Results: There were 62 prescriptions for irrational use of traditional Chinese medicine injections, accounting for 19.21%. In the unreasonable use of drugs, the top three were used for hyper-indications, overdosage or concentration, with improper solvent selection. Chinese medicine injection irrational drug adverse reactions occurred in 17.74% of adverse reactions, the main types of skin and accessory damage, cardiovascular system damage, digestive system reactions, nervous system reactions and systemic damage, involving drugs such as Shenmai injection , Compound Codonopsis injection, Aidi injection, Shuxuening needles, Dan red needles, thrombus pass, ginkgo membrane needle, Shenqi Fuzheng injection. Conclusion: The irrational use of traditional Chinese medicine injections in grassroots hospitals is more common. Management of traditional Chinese medicine injections should be intensified to improve the comprehensive level of clinicians. Strict control over the dosage and scope of use of traditional Chinese medicines should be taken to improve the safety of clinical injections. Treatment safety and effectiveness.