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目的研究内镜切除术联合疏肝和胃汤治疗胃多发息肉术后的临床疗效。方法将80例胃多发息肉患者随机分为治疗组和对照组,每组40例。两组均给予内镜下切除术和质子泵抑制剂治疗,治疗组结合疏肝和胃汤内服,疗程1个月。观察两组临床疗效、中医证候积分、血清胃蛋白酶原(PG)水平变化情况。结果 (1)治疗组临床疗效显著优于对照组(P<0.01)。(2)治疗后,两组中医症状积分均较治疗前显著降低(P<0.05),且治疗组低于对照组(P<0.05)。(3)治疗后,两组血清PGⅠ、PGR水平较治疗前均显著升高(P<0.05),且治疗组显著高于对照组(P<0.05)。结论内镜下切除术结合疏肝和胃汤治疗胃多发息肉可显著改善临床症状,促进胃黏膜修复。
Objective To study the clinical effect of endoscopic resection combined with Shugan Hewei decoction in the treatment of multiple polyp of stomach. Methods Eighty patients with multiple gastric polyps were randomly divided into treatment group and control group, 40 cases in each group. Both groups were given endoscopic resection and proton pump inhibitor treatment. The treatment group combined with Shugan and stomach decoction for one month. The clinical curative effect, TCM syndrome score and serum pepsinogen (PG) level were observed. Results (1) The clinical efficacy of the treatment group was significantly better than that of the control group (P <0.01). (2) After treatment, the score of TCM symptoms in both groups was significantly lower than that before treatment (P <0.05), and the treatment group was lower than the control group (P <0.05). (3) After treatment, the levels of serum PGI and PGR in both groups were significantly higher than those before treatment (P <0.05), and the treatment group was significantly higher than the control group (P <0.05). Conclusions Endoscopic resection combined with Shugan and Wei Tang can effectively improve the clinical symptoms and promote the repair of gastric mucosa.