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目的:探讨抗焦虑药物对肺结核患者伴发焦虑状态的治疗效果。方法:回顾性分析136例肺结核伴发焦虑状态住院患者,分为干预组(65例)及对照组(71例)。对照组采取常规抗结核治疗方案,干预组在此基础上加用抗焦虑药物氟哌噻吨美利曲辛(黛力新)(10.5mg qd丹麦灵北制药)。采用焦虑自评量表(Self-Rating Anxiety Scale SAS)在入院1周内及3个月、9个月后分别进行临床评估;同时在入院时及9个月后行胸片检查,观察病灶吸收情况。结果:对照组3个月及9个月后焦虑评分高于干预组(63.71±3.65,51.71±3.25,p<0.05)(65.21±4.56,47.53±5.21 p<0.05);对照组9个月后肺部情况病灶吸收较干预组差(30(46.9),37(61.7),p<0.05)。结论:1.肺结核患者焦虑状态发生率高2.早期应用抗焦虑药物能显著提高肺结核伴发焦虑状态患者临床治疗效果。
Objective: To investigate the therapeutic effect of anti-anxiety drugs on patients with pulmonary tuberculosis associated with anxiety. Methods: A retrospective analysis of 136 cases of tuberculosis patients with anxiety inpatients, divided into intervention group (65 cases) and control group (71 cases). In the control group, conventional anti-TB treatment was used. In the intervention group, flupentixol / dexamethasone (Deanxun), an anti-anxiety drug, was added to the intervention group (10.5 mg qd Danish Ling North Pharmaceutical). The clinical evaluation was performed within 1 week, 3 months and 9 months after admission on Self-Rating Anxiety Scale SAS. At the same time, the chest X-ray examination was performed at admission and 9 months later to observe the lesion absorption Happening. Results: The anxiety scores of the control group at 3 months and 9 months were higher than that of the intervention group (63.71 ± 3.65, 51.71 ± 3.25, p <0.05) (65.21 ± 4.56, 47.53 ± 5.21, p <0.05) Pulmonary lesions lesser than the intervention group (30 (46.9), 37 (61.7), p <0.05). Conclusion: 1. The incidence of tuberculosis patients with high anxiety state 2. Early use of anti-anxiety drugs can significantly improve the clinical treatment of patients with tuberculosis associated with anxiety.