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目的探讨多发脑内原发性淋巴瘤的特点,并分析误诊原因。方法回顾性分析6例经手术和病理证实的多发脑内淋巴瘤的MRI特点,并结合文献复习。结果6例淋巴瘤中病灶全位于幕上4例,幕下多发1例,幕上下多发1例。其中误诊为胶质瘤或转移瘤各2例,误诊为脑炎及脱髓鞘疾病各1例。MRI表现为T1WI等低信号,T2WI为稍高信号,增强扫描多数病灶表现为明显均匀强化。结论多发脑内原发性淋巴瘤MRI缺乏特征性,故易误诊。脑内实质性均匀强化为最常见表现。
Objective To investigate the characteristics of multiple primary brain lymphoma and to analyze the causes of misdiagnosis. Methods The MRI features of 6 cases of multiple intracranial lymphomas confirmed by surgery and pathology were retrospectively analyzed and reviewed. Results The lesions in 6 cases of lymphoma were all located on the supratentorial membrane in 4 cases, infraorbital multiple in 1 case and supratentorial in 1 case. Misdiagnosed as glioma or metastases in 2 cases, misdiagnosed as encephalitis and demyelinating disease in 1 case. MRI showed low signal such as T1WI, T2WI was slightly higher signal, enhanced scan most lesions showed markedly uniform enhancement. Conclusions Multiple brain MRI of primary lymphoma lacks characteristics and is therefore easily misdiagnosed. Substantial brain homogeneity is the most common manifestation.