对初诊的2型糖尿病患者33例进行4周的强化胰岛素治疗。并对治疗成功组患者随访1年。结果:4周的胰岛素强化治疗可以逆转初诊肥胖2型糖尿病患者β细胞的功能及改善他们的糖脂代谢指标。结论:短期胰岛素强化治疗对初诊肥胖2型糖尿病患者血糖、血脂控制有良好的疗效,并能够改善这些患者的胰岛β细胞功能。 Forty patients with newly diagnosed type 2 diabetes underwent intensive insulin therapy for 33 weeks. Patients in the treatment group were followed up for 1 year. RESULTS: Forty weeks of intensive insulin treatment reversed β-cell function and improved glucose and lipid metabolism in newly diagnosed obese type 2 diabetic patients. CONCLUSIONS: Short-term intensive insulin therapy has a good effect on the control of blood glucose and blood lipids in newly diagnosed obese type 2 diabetic patients and can improve pancreatic β-cell function in these patients.