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所谓肿瘤标记物是指肿瘤细胞由于基因表达的改变,所产生的肿瘤相关性产物。它们释放入血,使这些产物在血清中浓度增高,检测其浓度的变化作为诊断肝细胞癌(HCC)的依据,并可作为判断治疗效果与估计预后的一个指标。一、甲胎蛋白(AFP)测定:血清AFP测定是目前最有效的诊断试验之一,特异性强,敏感性高。如果阳性常常提示为HCC,假阳性少见。有报告重症肝炎、慢活肝(CAH)、肝硬变、先天性胆管闭锁症、酪氨酸血症、肝损伤、充血性肝大、共济失调毛细血管扩张症、妊娠头
The so-called tumor marker refers to a tumor-associated product produced by a change in gene expression of tumor cells. They are released into the bloodstream to increase the concentration of these products in the serum. Detection of changes in the concentration of these products is used as a basis for the diagnosis of hepatocellular carcinoma (HCC), and can be used as an index to judge the therapeutic effect and estimate the prognosis. First, the alpha-fetoprotein (AFP) determination: serum AFP determination is one of the most effective diagnostic tests, specificity, high sensitivity. If the positive is often prompted by HCC, false positives are rare. Reported severe hepatitis, chronic liver (CAH), liver cirrhosis, congenital biliary atresia, tyrosinemia, liver damage, congestive liver, ataxia telangiectasia, pregnancy head