患者,女,57岁。自出生时即发现左前臂比对侧略粗,无痛,活动正常。于30年前第1次妊娠时左前臂左手都有明显的增粗并有疼痛,逐渐出现畸形,并反复发作。近1年上述症状明显加重并伴功能障碍。检查左前臂左手明显增租畸形呈巨臂巨手状,关节僵直。压痛明显,局部肤色较深,感觉存在。X线示左前臂左手腕关节骨质明显吸收破坏,软组织密度增高。各项化验指 Patient, female, 57 years old. From the time of birth, the left forearm was found to be slightly thicker, painless, and normal than the opposite side. In the first pregnancy 30 years ago, the left forearm had obvious thickening and pain in his left hand, gradually deformed and recurrent. In the past 1 year, the above symptoms have obviously worsened and accompanied by dysfunction. Examine the left forearm with a significant increase in left-handed malformation as a massive giant arm, joint stiffness. The tenderness was obvious, and the skin was darker and felt. The X-ray shows that the left forearm and left wrist have obvious bone absorption and destruction, and the soft tissue density increases. Tests