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目的观察凯时、弥可保、高压氧联合治疗糖尿病神经病变的疗效。方法118例糖尿病神经病变患者随机分组对照观察,对照组给予维生素B1100mg、维生素B12500ug肌注每日一次、丹参20ml加入生理盐水250ml静滴每日一次,共4周。治疗组给予凯时10ug加入生理盐水100ml静滴每日一次、弥可保500ug肌注每日一次、高压氧治疗每周5次,总共4周。结果治疗组痛觉过敏、痛觉减退、肢体疼痛、肢体麻木、腱反射减退治疗后有效率达69.7﹪84.2﹪87.5﹪88.2﹪83.3﹪明显高于对照组(均P<0.05)。神经传导速度改善的有效率也有明显的提高(P<0.05)。结论凯时、弥可保、高压氧联合治疗糖尿病神经病变疗效显著。
Objective To observe the curative effect of combined treatment of diabetic neuropathy with Kay, Miocao and hyperbaric oxygen. Methods 118 cases of diabetic neuropathy patients were randomly divided into control group, the control group was given vitamin B1100mg, vitamin B12500ug intramuscular injection once daily, Salvia 20ml added saline 250ml intravenously once daily for 4 weeks. The treatment group given Kay when 10ug saline 100ml intravenously once a day, Mi Kebao 500ug intramuscular injection once daily, hyperbaric oxygen treatment 5 times a week for a total of 4 weeks. Results The effective rate of the treatment group was 69.7% 84.2% 87.5%, 88.2% 83.3%, which were significantly higher than that of the control group (all P <0.05) after the treatment of hyperalgesia, pain relief, limb pain, limb numbness and tendon reflex. The effective rate of nerve conduction velocity improvement was also significantly improved (P <0.05). Conclusion Kay, Mi Kebao, hyperbaric oxygen combined treatment of diabetic neuropathy significant effect.