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用新西兰白兔建立内毒素休克模型,以亲和免疫吸附清除循环中TNF,观察对动物心、肝、肺、肾组织中TNF和IL-8水平的影响。结果表明,能有效清除循环中TNF,并使组织中TNF和IL-8水平明显降低。
Endotoxic shock model was established in New Zealand white rabbits, and the circulating TNF was removed by affinity immunoadsorption. The levels of TNF and IL-8 in heart, liver, lung and kidney were observed. The results show that the cycle can effectively remove TNF, TNF and IL-8 levels were significantly reduced.