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目的观察自拟解毒退热汤结合西医治疗重症手足口病的临床疗效。方法 100例手足口病重症患者随机分为西药治疗和中西医治疗两组,每组50例。西药治疗应用抗病毒、支持、对症及激素冲击治疗;中西药治疗组在常规方法治疗的基础上,同时给予自拟解毒退热汤口服。比较治疗后两组患者症状及体征变化、临床疗效及不良反应等。结果与单纯西药治疗比较,中西药治疗对改善手足口病患儿体温、恶心呕吐及肢体抖动效果显著(P<0.01);治愈率中西医治疗组为52%,对照组为28%,差异有统计学意义(χ2=11.977,P<0.01)。两组患者治疗期间均未发生明显药物不良反应。结论自拟解毒退热汤汤联合西药治疗重症手足口病效果良好,能快速消除或缓解症状,缩短病程,改善血常规指标,治疗效果优于单纯西药治疗。
Objective To observe the clinical curative effect of self-detoxification antipyretic soup combined with western medicine in the treatment of severe hand-foot-mouth disease. Methods One hundred cases of HFMD were randomly divided into two groups: Western medicine treatment and Western medicine treatment, with 50 cases in each group. Western medicine treatment with antiviral, supportive, symptomatic and hormone shock treatment; Chinese and Western medicine treatment group in the conventional method of treatment based on the same time, given self-detoxification antipyretic oral. Compare the two groups of patients after treatment of symptoms and signs of change, clinical efficacy and adverse reactions. Results Compared with western medicine alone, Chinese and western medicine had significant effects on improving body temperature, nausea, vomiting and limb jitter in HFMD children (P <0.01). The cure rate was 52% in the treatment group and 28% in the control group Statistical significance (χ2 = 11.977, P <0.01). No significant adverse drug reactions occurred in both groups during treatment. Conclusion The self-made Detoxification Decoction Decoction combined with Western medicine treatment of severe hand-foot-mouth disease has a good effect, can quickly eliminate or relieve symptoms, shorten the course of disease, improve blood parameters, the treatment effect is superior to Western medicine alone.