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研究目的研究精神病患者HBV感染状况。研究设计调查并检测705例精神病患者HBV感染的血清学标志,并与287例医院职工的检测结果对比分析。研究单位附属精神病医院研究对象住院的精神病患者705例(精神分裂症667例,躁郁症38例)和医院职工287例。处理方法对705例精神病患者和287名医院职工分别抽取静脉血,用固象酶联免疫吸附法测定HBV感染的血清学标志。测定结果 HBV总感染率患者高于职工(P<0.01),精神病患者抗—HB_J及抗—HB_c阳性率女性高于男性。HB_sA_g阳性者中,患者 HB_eAg阳性率高于职工(P<0.01)。结论精神病患者HBV感染率高于医院职工,为防止院内交叉感染,对HB_sAg及HB_eAg阳性者应隔离治疗。
Study Objective To study the status of HBV infection in psychiatric patients. A total of 705 seropositive patients with psychosis were tested for serological markers of HBV infection and compared with the test results of 287 hospital staff. 705 psychiatric patients (667 schizophrenia, 38 bipolar disorder) and 287 hospital staff were included in the psychiatric hospital affiliated to the study unit. Methods 705 patients with mental illness and 287 hospital staff were drawn venous blood, respectively, by enzyme-linked immunosorbent assay HBV infection serological markers. The total HBV infection rate was higher than that of the workers (P <0.01). The positive rate of anti-HB_J and anti-HBc in the psychiatric patients was higher than that in the male. HBsAg positive patients, HBeAg positive rate in patients than workers (P <0.01). Conclusion The HBV infection rate of mental patients is higher than that of hospital staff. To prevent cross-infection in hospital, HBsAg and HBeAg-positive patients should be isolated and treated.