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30例慢性阻塞性肺病(COPD)缓解期住院患者,体外膈肌起搏(EDP)治疗2周后随机分为家庭继续治疗组15例和停止治疗组15例,分别于6周和16周进行随访。继续治疗期间,其最大口腔吸气压(MIP)、负荷呼吸时间(LT)、6min行走距离(6MWD)和膈肌移动度(DM)均有进一步改善(P<005),肺功能的改变不如呼吸肌功能明显,表现为VC、FEV1、FEV1/FVC的增大。停止治疗组16周后仅用6MWD、FEV1/FVC和深呼吸时DM较治疗前有改善,其余肺功能和呼吸肌功能指标均降到治疗前水平。提示家庭EDP继续治疗可巩固和进一步提高EDP的疗效。
Thirty patients with chronic obstructive pulmonary disease (COPD) undergoing remission were enrolled. After EDP treatment for 2 weeks, they were randomly divided into 15 consecutive family continuation groups and 15 stop treatment groups, followed up for 6 weeks and 16 weeks respectively . The MIP, LT, 6MWD and diaphragmatic muscle mobility (DM) were further improved (P <005) and the changes of lung function Not as good as respiratory muscle function, manifested as VC, FEV1, FEV1 / FVC increase. After 6 weeks of treatment, only 6MWD, FEV1 / FVC and deep breathing DM improved after treatment, and the rest of lung function and respiratory muscle function indexes dropped to pre-treatment level. Tip home EDP continued treatment can consolidate and further improve the efficacy of EDP.