论文部分内容阅读
目的探讨养阴清肺汤对非小细胞肺癌放射性肺炎的防治效果。方法50例非小细胞肺癌单纯放射治疗,应用10MV-X线外照射,模拟机下定位,包括原发灶、患侧肺门、纵隔,总剂量DT6500￣7000cGy。其中30例在治疗过程中应用养阴清肺汤1剂/d,另20例不用。结果治疗结束时,治疗组早期肺损伤8例,占26.6%,对照组早期肺损伤14例,占70%。两组对比差异有统计学意义(P<0.01)。放疗后3个月复查胸部X线片,治疗组照射野内肺纤维化面积超过50%12例,占40%;对照组15例,占75%。两组对比差异有统计学意义(P<0.05)。结论养阴清肺汤可预防肺癌放疗中的放射性肺损伤。
Objective To investigate the preventive and therapeutic effects of Yangyin Qingfei Decoction on radiation pneumonitis in non-small cell lung cancer. Methods Fifty patients with non-small cell lung cancer were treated with radiotherapy alone. The external beam was radiated by 10MV-X and simulated under the machine. The primary tumor, the hilar and the mediastinum were measured. The total dose of DT6500-7000cGy was obtained. Among them, 30 cases were treated with Yangyin Qingfei Decoction 1 / d during the course of treatment, and the other 20 cases were not used. Results At the end of treatment, 8 cases of early lung injury in the treatment group (26.6%) and 14 cases of early lung injury in the control group (70%). The difference between the two groups was statistically significant (P <0.01). Thoracic radiographs were reviewed at 3 months after radiotherapy. In the treatment group, the area of lung fibrosis exceeded 50% in 12 cases (40%), and that in the control group (75%). The difference between the two groups was statistically significant (P <0.05). Conclusion Yangyin Qingfei Decoction can prevent radiation-induced lung injury during radiotherapy of lung cancer.