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目的探讨使用双水平气道正压通气(Bipap)治疗轻、中度慢性阻塞性肺病急性发作期并II型呼吸衰竭,间歇性使用的次数及时间与疗效的关系。方法:对90例慢性阻塞性肺疾病轻、中度急性发作并II型呼吸衰竭患者随机分为3组,采用常规治疗同时,均使用Bipap呼吸机通气,I组1次/天,4小时/次;II组2次/天,2小时/次;III组4次/天,1小时/次。治疗3天后,比较3组治疗前后的动脉血气、呼吸频率及心率变化情况。结果:II组较其它两组PO2、PCO2及呼吸频率改善较明显,差异有显著性(P<0.05)。结论:短期间歇使用Bipap治疗轻、中度慢性阻塞性肺病并II型呼吸衰竭,以每天使用2次较为适合。
Objective To explore the relationship between the use of Bipap in the treatment of mild and moderate chronic obstructive pulmonary disease (COPD) and type II respiratory failure, the number and duration of intermittent use and curative effect. Methods: Ninety patients with mild to moderate chronic obstructive pulmonary disease (COPD) and type II respiratory failure were randomly divided into three groups. All the patients were treated with Bipap ventilator, once a day, once a day for 4 hours, Group II 2 times / day, 2 hours / time; Group III 4 times / day, 1 hour / time. After 3 days of treatment, arterial blood gas, respiratory rate and heart rate were compared between the three groups before and after treatment. Results: Compared with the other two groups, the PO2, PCO2 and respiration rate of group II improved more obviously, the difference was significant (P <0.05). CONCLUSIONS: Short-term intermittent use of Bipap for mild to moderate chronic obstructive pulmonary disease and type II respiratory failure is best used twice daily.