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甲硝唑在临床上应用非常广泛,特别是应用于胃肠道、妇科手术后的厌氧菌感染,现简述在口腔颌面外科的应用。1 临床资料 一年来被治10例病人,下颌骨骨折5例,上颌骨骨折1例,T_8冠周炎并嚼肌间隙感染、口底蜂窝织炎各2例。典型病例:例1,男,32岁,因车祸下颌骨右颊部骨折。入院后行下颌骨内外固位术,术后用青霉素1g加入5％GNS 500 ml,0.5％甲硝唑 250ml及维生素 C2g,10％KCI 20ml静滴。1次/d,2d后夜间腹部不适疼痛,口干,食欲不振、头痛、头晕等,3d后上述症状加重,立即给以停药(甲硝唑),当日即未出现上述症状。例2,女,19岁,因患口低蜂窝
Clinical application of metronidazole is very wide, especially for gastrointestinal, gynecological anaerobic infections, is now outlined in the application of oral and maxillofacial surgery. 1 clinical data over the past year were treated 10 patients, 5 cases of mandibular fracture, maxillary fracture in 1 case, T_8 pericoronitis and chewing muscle gap infection, the bottom of the mouth cellulitis in 2 cases. Typical cases: Example 1, male, 32 years old, due to a car accident mandibular right cheek fracture. After admission, mandibular internal and external reattachment was performed. After operation, penicillin 1g was added to 500ml of 5% GNS, 250ml of 0.5% metronidazole and 20ml intravenous infusion of vitamin C2g and 10% KCI. 1 time / d, abdominal discomfort after 2d night pain, dry mouth, loss of appetite, headache, dizziness, etc. 3d after the above symptoms aggravate, immediately to the withdrawal (metronidazole), the same day that the above symptoms do not appear. Example 2, female, 19 years old, suffering from mouth low cellular