冠脉血流重建是保护缺血心肌的重要手段之一,但是,关于其效果一直存在着争议,本实验的目的在于复制家兔实验性心肌梗塞及再灌注的模型;观察再灌注对于左室心肌收缩性能及血液动力学影响的动态过程;并试图对其变化机制进行初步探讨。 实验采用25只家兔,在乌拉坦全麻下开胸进行实验,采用RM-46四导生理记录仪连续、同前步记录Ⅱ导心电、左室收缩压峰 Coronary flow remodeling is one of the important means to protect the ischemic myocardium. However, there is controversy about its effect. The purpose of this experiment is to duplicate the model of experimental myocardial infarction and reperfusion in rabbits. To observe the effects of reperfusion on left ventricular Myocardial contractility and hemodynamic effects of the dynamic process; and try to explore the mechanism of its change. Twenty-five rabbits were used in the experiment, and thoracotomy was performed under general anesthesia with urethane. RM-46 four-lead physiologic recorder was used to record continuous,