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我院于1994年8月～1995年9月应用帕金宁控释片治疗帕金森综合征23例,现将帕金宁控释片治疗帕金森综合征的疗效报道如下。 1 临床资料 本组23例中男19例,女4例,年龄57岁～78岁,平均61.34±5.87岁。病程1年～15年,平均7.71±4.15年。23例均为高血压动脉硬化性帕金森综合征。其中门诊17例,住院6例。住院者均因急性脑梗塞伴帕金森综合征入院治疗。 除6例具有急性脑梗塞的体征外,23例均有不同程度四肢肌张力增高,其中呈齿轮样肌张力增高18例,铅管样肌张力增高5例;呈假面具有17例,静止震颤者20例,慌张步态14例,碎步态者8例,正常步态者1例,行走时上肢均呈不协调摆动。 23例中18例已服用左旋多巴250mg,每天3次,5例已服用美多巴250mg,每天3次,均因症状未能控制
In our hospital from August 1994 to September 1995 application of Parkinson’s controlled release tablets Parkinson’s disease in 23 cases, now Parkinson’s controlled release tablets in the treatment of Parkinson’s disease reported as follows. 1 Clinical data The group of 23 patients, 19 males and 4 females, aged 57 to 78 years, mean 61.34 ± 5.87 years. Duration of 1 year to 15 years, an average of 7. 71 ± 4. 15 years. 23 cases were all atherosclerosis of Parkinson’s disease. Among them outpatient 17 cases, hospitalized 6 cases. Inpatients were hospitalized for acute cerebral infarction with Parkinson’s syndrome. Except 6 patients with signs of acute cerebral infarction, 23 patients had varying degrees of limb muscle tension increased, which showed gear-like muscle tone increased in 18 cases, lead tube-like muscle tension increased in 5 cases; 20 cases, 14 cases of panic gait, 8 cases of broken gait, 1 case of normal gait, the upper limbs were walking uncoordinated swinging. Of the 23 patients, 18 had taken levodopa 250 mg three times daily, and 5 had taken metoprolol 250 mg three times a day, both of whom were unable to control their symptoms