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目的探讨乳腺癌改良根治加带蒂背阔肌皮瓣移植术在针对局部晚期乳腺癌的治疗价值。方法阳江市人民医院乳腺科2008年12月至2010年12月对25例癌肿侵犯皮肤的局部晚期乳腺癌进行新辅助化疗后,予乳腺癌改良根治加带蒂背阔肌皮瓣移植术治疗。结果所有的病例治疗后随访1年,25例患者手术无1例出现严重并发症,患者生活质量佳,21例复查乳腺彩超、腹部B超、胸片、全身骨扫描等检查,未发现局部和淋巴结复发及远处转移,2例出现骨转移,1例出现腋窝复发,1例肺转移后死亡。结论乳腺癌改良根治加带蒂背阔肌皮瓣移植术针对部分癌肿侵犯皮肤的局部晚期乳腺癌有较重大的临床应用。
Objective To investigate the therapeutic value of modified radical mastectomy combined with latissimus dorsi flap transplantation for locally advanced breast cancer. Methods From December 2008 to December 2010, 25 cases of locally advanced breast cancer with cancer-infiltrated skin were treated with neoadjuvant chemotherapy after modified radical mastectomy and latissimus dorsi flap transplantation . Results All patients were followed up for 1 year after treatment. None of the 25 patients had serious complications in one case, and the quality of life of the patients was good. 21 cases were examined by ultrasonography, ultrasonography, chest X-ray, and whole-body bone scan. Lymph node recurrence and distant metastasis, two cases of bone metastases, one case of axillary recurrence, one case of lung metastasis and death. Conclusion Modified radical mastectomy and pedicel with latissimus dorsi flap transplantation have some serious clinical applications in the treatment of locally advanced breast cancer with some of the cancers infiltrating the skin.