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肝星状细胞(hepatic stellate cell,HSC)与肝纤维化形成密切相关,使得HSC被广泛地关注,肝纤维化是慢性肝病共有的病理改变,是肝脏对慢性损伤的一种修复反应,其特征为细胞外基质(extracellular matrix,EMC)的过度表达和异常沉积。活化的HSC是肝纤维化发生中EMC的主要来源,是肝纤
Hepatic stellate cells (HSC) are closely related to the formation of hepatic fibrosis, making HSC widely concerned. Liver fibrosis is a common pathological change in chronic liver disease and is a repair reaction of the liver to chronic injury. Its characteristics It is overexpression and abnormal deposition of extracellular matrix (EMC). Activated HSC is the main source of EMC in the development of hepatic fibrosis and is liver fibrosis