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为了研究加味玉屏风散抗哮喘的作用机制,本实验测定了加味玉屏风散对哮喘大鼠红细胞中的丙二醛(MDA)、共轭双烯(CD)以及谷光甘肽过氧化物酶(GSH-Px)、过氧化氨酶(Cat)变化的影响。观察结果哮喘大鼠血中MDA、CD含量明显升高,GSH-Px、Cat活性明显降低,而中西药均能降低MDA、CD含量,提高GSH-Px和Cat活性,且中药组效果明显优于西药组。表明加味玉屏风散具有调节过氧化反应与抗氧化酶之间平衡的功能,对支气管哮喘起到一定的防治作用。
In order to study the mechanism of Jiawei Yupingfeng San on anti-asthma, we measured the effects of Jiawei Yupingfeng Powder on malondialdehyde (MDA), conjugated diolefin (CD) and glutathione peroxidase GSH-Px), peroxidase (Cat) changes. The results showed that the contents of MDA and CD in serum of asthmatic rats were significantly increased, the activities of GSH-Px and Cat were significantly decreased, while the contents of MDA and CD were decreased, and the activities of GSH-Px and Cat were increased Western medicine group. It shows that flavored Yupingfengsan has the function of regulating the balance between peroxidation and antioxidant enzymes and plays a role in prevention and treatment of bronchial asthma.