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目的 探讨体感诱发电位 (somatosensoryevokedpotentials,SEPs)在评价脑卒中急性期患者肢体运动功能中的作用 ,及其与临床评估在预测脑卒中后肢体运动功能恢复中的价值。方法 脑卒中急性期患者 2 5例 ,在发病 7d内和住院 30d时分别进行上、下肢SEPs检测 ,同时进行上、下肢Fugl Meyer评分 (F M评分 ) ,对照组 1 8例发病 7d内进行上、下肢SEPs检测 ,比较两组患者SEPs的潜伏期 ,并将病例组在发病 7d内和住院 30d时的SEPs潜伏期与F M评分进行相关分析 ;根据病例组是否存在感觉障碍 ,分成有和无感觉障碍组 ,比较两组潜伏期的变化。结果 病例组和对照组上、下肢SEPs潜伏期差异有显著性意义 ,病例组入院时和住院 30d时SEPs潜伏期 (除P1 4、N30 、P2 2 、N35)与上肢 (包括腕、手 )和下肢F M评分有相关性。有感觉障碍组上、下肢SEPs和各电位潜伏期较无感觉障碍组普遍延长。结论 脑卒中急性期患者 ,尤其是存在感觉障碍者SEPs潜伏期的改变较为敏感 ,并与F M评分有相关性 ,说明SEPs在预测脑卒中急性期患者肢体运动功能恢复中有一定的价值
Objective To investigate the role of somatosensory evoked potentials (SEPs) in the assessment of motor function of limbs in patients with acute stroke and its value in predicting the recovery of limb motor function after stroke. Methods Twenty-five patients with acute stroke were enrolled in this study. SEPs of the upper and lower extremities were detected within 7 days of onset and 30 days of hospitalization respectively. Fugl Meyer scores (FM scores) of both upper and lower limbs were also measured. In the control group, SEPs of the lower extremity were detected to compare the incubation period of SEPs between the two groups. Correlation analysis was made between the latency of SEPs and the score of FM in the case group within 7 days and 30 days. According to the presence or absence of sensory disorder in the case group, The change of latency between the two groups was compared. Results There were significant differences in the latency of SEPs in the upper and lower extremities between the case group and the control group. The latency of SEPs (except P1 4, N30, P2 2, N35) and upper limbs (including wrists and hands) and legs FM Scores are relevant. Sensory dysfunction group, lower extremity SEPs and potential latency than the general extension of the group without sensation. Conclusions The changes of the latency of SEPs in acute stroke patients, especially those with sensory disturbances, are more sensitive and correlated with F M scores, indicating that SEPs have some value in predicting limb motor function recovery in acute stroke patients