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用 KM小鼠测定克拉霉素胶囊剂的 L D50 ,小鼠口服 L D50 大于 5 g/ kg;小鼠腹腔注射 L D50 为 1.16 g/ kg,95 %可信限为 1.0 0～ 1.35 g/ kg。克拉霉素胶囊剂急性毒性试验@于德志$青岛市药品检验所!青岛266071@莫宗琪$济南军区药剂研究中心!青岛266071@吴
The L D50 of clarithromycin capsules was measured in KM mice, and the oral LD50 in mice was greater than 5 g / kg. The L D50 in mice was 1.16 g / kg and the 95% confidence limit was 1.0 0-1.35 g / kg . Acute Toxicity Test of Clarithromycin Capsules @ Yu Dezhi $ Qingdao Institute of Drug Control, Qingdao 266071 @ @ @ Muzhong Qi Pharmacy Research Center of Jinan Military Region! Qingdao 266071 @ Wu