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应用甲基强的松龙(Methylprednisolone)超大剂量静脉注射治疗一些肾疾患,即类固醇激素的冲击疗法(Pulse therapy),可获得显著疗效。晚近日本肾脏病学会根据10个单位约130例的临床报告结果,亦认为是治疗肾小球疾患的积极疗法之一。现仅就最近的文献资料综述如下: 一、给药方法Methylprednisolone 15～20mg/kg/日或1000mg/日,静脉慢注(20分钟以上),连续3天,必要时,隔1～2周可再用,以后口服强的松(Prednisone)30～40mg/日×4周,然后以同样剂量隔天1次共5个月,再后逐渐减药以至停药。亦有作者使用强的
The use of methylprednisolone (IV) as a large dose intravenous injection for the treatment of a number of kidney disorders, the steroid hormone therapy (Pulse therapy), achieved significant results. Recently, the Japanese Society of Nephrology is also considered as one of the active treatments for glomerular disorders based on the clinical reports of about 130 cases in 10 units. The only recent literature is summarized as follows: First, the method of administration Methylprednisolone 15 ~ 20mg / kg / day or 1000mg / day, slow venous injection (20 minutes) for 3 days, if necessary, every 1 to 2 weeks And then oral prednisone (Prednisone) 30 ~ 40mg / day × 4 weeks, and then the same dose every other day for a total of 5 months, and then gradually reduce the drug or withdrawal. Some authors also use strong