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颅内骨肿瘤为中枢神经系统（ＣＮＳ）罕见肿瘤，本文报告６例，占我院２１２１例ＣＮＳ肿瘤的０．２８％，其中骨肉瘤成分为主的肿瘤、骨巨细胞瘤各１例，软骨肉瘤、骨软骨瘤各２例。患者年龄除２例外，均在２８岁以下。骨巨细胞瘤病程最长，达１０余年。所有肿瘤均在５ｃｍ以上，其中最大者为颅中凹骨软骨瘤，达９ｃｍ×７ｃｍ×７ｃｍ。骨肉瘤成分位于与颅骨无关的右颞顶叶脑实质内，极罕见。本组部分病例经电镜及免疫组织化学研究（ＧＦＡＰ、Ｖｉｍｅｎｔｉｎ、ＥＭＡ、Ｋｅｒａｔｉｎ）证实肿瘤来源。本文分别讨论了四种肿瘤的发病情况、病理学特征及组织起源等。
Intracranial bone tumors are rare tumors of the central nervous system (CNS). Six cases were reported in this paper, accounting for 0.28% of 2121 CNS tumors in our hospital. One of them was osteosarcoma, one was giant cell tumor of bone, Sarcoma, osteochondroma in 2 cases. The patient’s age except 2 cases were below 28 years old. Giant cell tumor of bone disease the longest, up to 10 years. All tumors were more than 5cm, of which the largest cranial osteochondroma, up to 9cm × 7cm × 7cm. Osteosarcoma component is located in the skull and right parietal lobe parietal parenchyma, extremely rare. Some cases in this group by electron microscopy and immunohistochemistry (GFAP, Vimentin, EMA, Keratin) confirmed the source of the tumor. This article discusses the incidence of four kinds of tumors, pathological features and tissue origin.