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全球淋巴丝虫感染者约占人口总数的2％。Pani等认为性别是影响淋巴丝虫感染的重要因素。Brabin提出妊娠是导致育龄妇女微丝蚴率和微丝蚴密度下降原因的假说。 本文作者等用数学模型分析了妊娠是否足以影响淋巴丝虫感染。研究的样本随机选自巴布亚新几内亚的东塞皮克省的一个伊维菌素和乙胺嗪防治班氏丝虫病试点的社区。微丝蚴密度计数系据1994年该试点治疗前对2219名5岁以上居民夜间采血1ml薄膜过滤法的结果。设平均微丝蚴密度μ作为年龄和性别的连续函数符合负二项分布,按公式计算出概率并画出曲线图。从试点人口统计资料获得妇女的生育记录,按采血后9个月内是否生育来确定妊娠。为每一名妊娠妇
Global lymphatic filariasis accounts for about 2% of the total population. Pani, etc. that sex is an important factor affecting lymphatic filariasis infection. Brabin proposed pregnancy is the leading cause of women of childbearing age microfilariae and Microfilaria density decline hypothesis. The authors used mathematical models to analyze whether pregnancy is sufficient to affect lymphatic filariasis infection. The study samples were randomly selected from a community of Ivermectin and Diethylzine for controlling Bancroftian filariasis in Pudong, Papua New Guinea. Microfilaria density count line According to the pilot in 1994 before the treatment of 2219 residents over the age of 5 night filming 1ml membrane filtration results. Set the average microfilariae density μ as a function of age and sex in line with the negative binomial distribution, according to the formula to calculate the probability and draw the curve. Women’s fertility records are obtained from the pilot demographic data, and pregnancy is determined by whether or not they have been born within 9 months after blood sampling. For every pregnant woman