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In the model rat with precancerous lesion of stomach induced by the combined method of insertion ofa spring into the pylorus and high salt hot paste,effects of San Qi (三七 Radix Notoginseng) on gastricsecretion and protective factors of stomach were investigated.The results indicated that gastricsecretion,gastric mucosal blood flow (GMBF) and aminohexose content lowered significantly,andmalondialdehyde (MDA) increased significantly (P<0.01) in the model group as compared with thenormal group;after treatment with San Qi Powder for 12 weeks,both gastric secresion and GMBFincreased,and MDA content decreased as compared with the negative control group (P<0.01),withno significant increase of aminohexose content.It is suggested that San Qi (三七 Radix Notoginseng)may improve gastric secretion,and that increase of GMBF and antagonism against the lesion ofoxygen free radicals are possibly one of its mechanisms.
In the model rat with precancerous lesion of stomach induced by the combined method of insertion of a spring into the pylorus and high salt hot paste,effects of San Qi (三七 Radix Notoginseng) on gastricsecretion and protective factors of stomach were investigated.The results indicated That gastricsecretion,gastric mucosal blood flow (GMBF) and aminohexose content decreased significantly,andmalondialdehyde (MDA) increased significantly (P<0.01) in the model group as compared with thenormal group;after treatment with San Qi Powder for 12 weeks,both gastric secresion And GMBFincreased,and MDA content decreased as compared with the negative control group (P<0.01),with no significant increase of aminohexose content.It is suggested that San Qi(三七 Radix Notoginseng)may benefits975 secretion,and that increase of GMBF and Antagonism against the lesion ofoxygen free radicals are possibly one of its mechanisms.