中枢神经系统的损伤，包括原发性和继发性损伤。继发性损伤中由许多内源性介质、缺氧缺血和糖利用障碍等诱发，而内源性神经介质特别是内源性阿片肽的释放增加，能加重中枢神经系统的继发性损害，进而导致语言、肢体障碍、神志改变甚至昏迷。缺血性脑梗死为内科急重症，其预后 Central nervous system damage, including primary and secondary injuries. Secondary damage is induced by many endogenous mediators, hypoxia-ischemia, and disorders of carbohydrate utilization, and the release of endogenous neurotransmitters, particularly endogenous opioid peptides, can exacerbate secondary damage to the central nervous system , Leading to language, physical disorders, mental changes or even coma. Ischemic cerebral infarction severe acute illness, its prognosis