弓形虫是寄生于人和动物组织细胞内的原虫。入侵人体后,如果免疫力正常,弓形虫则以胞囊的形式存在,个体呈无症状的带虫状态。在妊娠早期,由于促性腺激素、孕酮、乙烯雌酚分泌增多,会明显增加对自然杀伤细胞(NK)的抑制作用。免疫功能下降,并可能激发原来的潜在感染。如果长期或反复受到弓形虫的感染,常会导致流产、死胎、早产、脑积水、无脑儿等严重畸形,甚至贻害终生。弓形虫感染对优生优育关系重大,现将近年来有关文献综述如下。 弓形虫对妊娠胚胎组织细胞生长发育的影响:弓形虫属人兽共患病的原生球虫,猫是其终宿主。与猫狗等动物密切接触,吃生肉或半熟的肉制品,尤其是食用洗涤不干净的水果、蔬菜等均可被弓形虫感染。此外,国外流行病学统计报告,煮熟的肉制品也可传播弓形虫病。虽然高浓度的盐会降低PCR法及组织培养的敏感性,但还是在煮熟的肉食品中检测出弓形虫。因此必须尽快找到准确检测熟食中弓形虫的方法。弓形虫经口侵人人体消化道,在消化酶的作用下,脱去外壳释放出裂殖体在肠上皮细胞内寄生。或在血液中吞噬及多核酸球内寄生。并随血流侵入胎盘及胎体血液循环内;也易于脑细胞及发育不成熟的幼稚细胞内繁衍后代,损害胚胎细胞生长发育。 Toxoplasma gondii parasites parasites in human and animal tissue cells in the protozoan. Invaded the human body, if the immunity is normal, toxoplasmosis is in the form of cysts, the individual was asymptomatic state of insects. In early pregnancy, as gonadotropin, progesterone, diethylstilbestrol increased secretion, will significantly increase the natural killer (NK) inhibition. Immune function decline, and may stimulate the original potential infection. If long-term or repeated by Toxoplasma gondii infection, often lead to miscarriage, stillbirth, premature birth, hydrocephalus, anencephalic and other serious deformities, and even harming life. Toxoplasma gondii infection has a great relationship with prenatal and postnatal care, the relevant literature review in recent years is as follows. Effects of Toxoplasma gondii on the Growth and Development of Pregnant Embryonic Tissue Tissues: Toxoplasma gondii zooplankton native to coccidia, the cat is its ultimate host. In close contact with animals such as dogs and cats, eat raw meat or semi-cooked meat products, especially food washing dirty fruits and vegetables can be Toxoplasma infection. In addition, epidemiological reports abroad, cooked meat products can also transmit toxoplasmosis. Toxoplasma gondii was detected in cooked meat products, although high concentrations of salt reduced susceptibility to PCR and tissue culture. Therefore, we must find an accurate detection of Toxoplasma grate in cooked food as soon as possible. Toxoplasma gondii invade the human gastrointestinal tract, under the action of digestive enzymes, the shell is released to release schizonts in intestinal epithelial cells in the parasitism. Or phagocytosis in the blood and multi-nucleic acid ball within the parasitism. And with the bloodstream invade the placenta and carcass blood circulation; also easy to brain cells and immature naive cells multiply offspring, damage embryonic cell growth and development.