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目的探讨早期干预治疗危重早产儿应激反应的临床效果与预后。方法 316例危重早产儿随机分为两组。早期干预组危重早产儿在应激反应发生前密切监测血糖的变化、控制糖速、糖浓度、合理应用抗生素、肠道益生菌和胃肠黏膜保护剂,监测危重症的进程。结果早期干预治疗后,与未早期干预组相比,可明显降低危重早产儿单纯应激性高血糖、单纯应激性溃疡以及同时出现两种应激反应的发生率(P均<0.05)。未早期干预组未给予任何干预治疗措施。结论危重早产儿应激反应,早期干预治疗后,明显降低应激反应后严重并发症的发生率,从而降低了危重早产儿的致残率、病死率,明显改善预后,提高生活质量。
Objective To investigate the clinical effects and prognosis of early intervention in the treatment of critically ill preterm children with stress. Methods 316 cases of critically ill premature children were randomly divided into two groups. Early intervention in critically ill preterm children in the stress response before close monitoring of blood glucose changes, control of sugar and sugar concentrations, the rational use of antibiotics, probiotics and gastrointestinal mucosal protective agent to monitor the progress of critically ill patients. Results Compared with the non-intervention group, the early stress-induced hyperglycemia, simple stress ulcer and the simultaneous occurrence of both stress reactions in preterm infants with early intervention significantly decreased (P <0.05). No early intervention group did not give any intervention treatment. Conclusion The stress response in premature infants is very serious. After the early intervention, the incidence of severe complications after stress reaction is significantly reduced, which can reduce the morbidity and mortality of critically ill premature infants, improve the prognosis and improve the quality of life.