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目的探讨慢性化脓性中耳炎病原菌分布及药敏试验结果。方法收集100例慢性化脓性中耳炎患者资料,分析耳脓性分泌物的病原菌培养及药敏试验结果。结果 100例患者,35例分离出病原菌,占35.0%,铜绿假单胞菌与金黄色葡萄球菌检出率最高。铜绿假单胞菌对头孢哌酮敏感率为90.9%,而对于哌拉西林、头孢他定、阿米卡星、注射用亚胺培南西司他丁钠的敏感率均为100.0%。金黄色葡萄球菌对阿米卡星和阿莫西林的敏感率均为100.0%,而对于青霉素的耐药率高达90.0%。结论铜绿假单胞菌与金黄色葡萄球菌为慢性化脓性中耳炎患者的主要致病菌,临床需综合病原菌检验及药敏试验结果合理选择抗生素,预防抗生素滥用。
Objective To investigate the distribution of pathogenic bacteria in chronic suppurative otitis media and drug susceptibility test results. Methods The data of 100 patients with chronic suppurative otitis media were collected, and the pathogen culture and drug susceptibility test results of the secretion of purulent secretions were analyzed. Results 100 cases of patients, 35 cases isolated pathogens, accounting for 35.0%, Pseudomonas aeruginosa and Staphylococcus aureus highest detection rate. The susceptibility of Pseudomonas aeruginosa to cefoperazone was 90.9%, while the sensitivity to piperacillin, ceftazidime, amikacin, and imipenem plus cilastatin sodium for injection was 100.0%. The susceptibilities of Staphylococcus aureus to amikacin and amoxicillin were all 100.0%, while those to penicillin were as high as 90.0%. Conclusion Pseudomonas aeruginosa and Staphylococcus aureus are the main pathogenic bacteria in patients with chronic suppurative otitis media. In order to prevent the abuse of antibiotics, rational selection of antibiotics should be based on the comprehensive pathogenic bacteria test and drug susceptibility test.