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目的:探讨高同型半胱氨酸(Hcy)血症与脑梗死的关系。方法:测定84例急性缺血性卒中患者与70例健康体检者血液同型半胱氨酸(Hcy)水平比较,并对脑卒中传统危险因素进行相关分析。结果:急性缺血性卒中组Hcy明显高于对照组,差异有统计学意义(P<0.05)。病例组中Hcy水平与血压、血脂、血糖高低及脑梗死病灶的大小无明显相关性,差异无统计学意义(P>0.05)。结论:高同型半胱氨酸血症与缺血性卒中发生成正相关,是脑梗死发生的一个独立危险因素。
Objective: To investigate the relationship between hyperhomocysteinemia and cerebral infarction. Methods: The plasma levels of homocysteine (Hcy) were measured in 84 patients with acute ischemic stroke and 70 healthy subjects, and the related risk factors of stroke were analyzed. Results: Hcy in acute ischemic stroke group was significantly higher than that in control group (P <0.05). The level of Hcy in the case group had no significant correlation with the blood pressure, blood lipids, the level of blood glucose and the size of the cerebral infarction. The difference was not statistically significant (P> 0.05). Conclusion: Hyperhomocysteinemia is positively correlated with the occurrence of ischemic stroke and is an independent risk factor for cerebral infarction.