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目的探讨内镜下氩离子凝固术治疗Barrett食管的临床疗效。方法选取赣州市人民医院消化内科2013年4月—2014年12月接收的81例Barrett食管患者,随机分为试验组(48例)与对照组(33例)。试验组患者给予内镜下氩离子凝固术治疗,术后口服埃索美拉唑、铝碳酸镁颗粒;对照组患者给予埃索美拉唑、铝碳酸镁颗粒治疗。3个月后复查,观察患者是否存在残留Barrett食管,若有残留对患者再次行氩离子凝固术治疗。比较两组临床疗效、残留及复发情况。结果对照组治愈率低于试验组,残留率、复发率高于试验组,差异有统计学意义(P<0.05)。结论内镜下氩离子凝固术治疗Barrett食管不仅操作简单、治愈率高,同时复发率低、并发症少、安全性高。
Objective To investigate the clinical efficacy of endoscopic argon plasma coagulation in the treatment of Barrett’s esophagus. Methods 81 patients with Barrett’s esophagus received from Department of Gastroenterology, People’s Hospital of Ganzhou from April 2013 to December 2014 were randomly divided into experimental group (48 cases) and control group (33 cases). Patients in the test group were given endoscopic argon plasma coagulation, and esomeprazole and aluminum magnesium carbonate granules were given orally after surgery. Patients in the control group were given esomeprazole and aluminum magnesium carbonate granules. 3 months after the review to observe the presence or absence of residual Barrett esophagus patients, if residual residual argon ion coagulation therapy in patients with re-treatment. The clinical efficacy, residual and recurrence were compared between the two groups. Results The cure rate of the control group was lower than that of the test group, the residual rate and recurrence rate were higher than the experimental group, the difference was statistically significant (P <0.05). Conclusion Endoscopic argon plasma coagulation for Barrett’s esophagus is not only simple, high cure rate, low recurrence rate, few complications and high safety.