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目的监测孕产妇及0~8月龄婴儿麻疹胎传抗体水平,探讨婴儿麻疹胎传抗体水平提前消失的原因。方法在铜川市随机抽取孕产妇及0~8月龄婴儿采集静脉血,用酶联免疫吸附试验(ELISA)检测麻疹IgG抗体。结果170对母婴母亲抗体阳性率87.06%,平均GMC为884.83 mIU/ml;婴儿抗体阳性率94.12%,平均GMC为1 211.51 mIU/ml,母亲与其婴儿抗体水平之间密切相关。0~8月龄幼儿麻疹胎传抗体随月龄增加迅速下降,大多在3~4月龄时抗体水平转阴,已成为麻疹易感者。结论孕母与其婴儿麻疹抗体水平密切相关,麻疹胎传抗体提前消失一方面是由于育龄期妇女麻疹抗体水平不高,另一方面是婴儿胎传抗体递减太快的缘故。
Objective To monitor the levels of fetal antibody in measles of pregnant women and infants aged 0 ~ 8 months and explore the reasons why the level of fetal antibody in infant measles disappears earlier. Methods The pregnant women and infants aged 0 ~ 8 months were randomly selected in Tongchuan City to collect the venous blood and the measles IgG antibody was detected by enzyme - linked immunosorbent assay (ELISA). Results The positive rate of antibody to maternal and infant mothers was 87.06% and the average GMC was 884.83 mIU / ml. The positive rate of infant antibody was 94.12% and the mean GMC was 1111.51 mIU / ml. There was a close correlation between maternal and infant antibody levels. 0 to 8 month-old children with measles fetal antibodies decreased rapidly with increasing age, mostly in 3 to 4 months of age when the antibody levels turned negative, has become susceptible to measles. Conclusion The pregnant mothers and their infant measles antibody levels are closely related to disappearance of measles premature antibodies on the one hand due to the low level of measles antibody in women of childbearing age on the other hand is due to the decline in infant fetal antibodies too fast.