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目的探讨乌司他丁联合醒脑静治疗急性脑出血的临床疗效。方法选取广安市人民医院2016年收治的急性脑出血患者114例,随机将其分为单用组57例和联合组57例。两组患者均予以常规基础治疗,在此基础上单用组患者予以醒脑静注射液治疗,联合组患者予以乌司他丁联合醒脑静注射液治疗,两组患者均连续治疗14 d。比较两组患者临床疗效、治疗后神经功能缺失程度量表(NDS)评分、脑水肿面积及不良反应发生情况。结果联合组总有效率高于单用组(P<0.05)。联合组患者NDS评分、脑水肿面积低于单用组(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论乌司他丁联合醒脑静治疗急性脑出血的临床疗效确切,可有效改善患者的神经功能,缩小脑水肿面积。
Objective To investigate the clinical efficacy of ulinastatin combined with xingnaojing in treating acute cerebral hemorrhage. Methods 114 patients with acute cerebral hemorrhage admitted to Guang’an People’s Hospital in 2016 were randomly divided into 57 patients in combination group and 57 patients in combination group. Both groups were treated with conventional basic therapy. On this basis, the patients in the single group were treated with Xingnaojing injection. The patients in the combined group were treated with ulinastatin combined with Xingnaojing injection. The patients in both groups were treated continuously for 14 days. The clinical efficacy, NDS score, area of brain edema and incidence of adverse reactions were compared between the two groups. Results The total effective rate in the combined group was higher than that in the single group (P <0.05). NDS score and brain edema area in the combined group were lower than those in the single group (P <0.05). Two groups of patients with adverse reactions, the difference was not statistically significant (P> 0.05). Conclusion The combination of ulinastatin and xingnaojing is effective in treating acute cerebral hemorrhage. It can effectively improve the neurological function and reduce the area of cerebral edema.