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目的了解抗菌药物联合干预成效,为深入开展抗菌药物临床应用专项整治工作及医院感染控制提供依据。方法由临床药学部及医院感染科对2013年1-12月26 686例住院患者抗菌药物使用率与医院感染率、例次感染率、漏报率及治疗使用抗菌药物病原学送检率等指标进行调查、汇总、分析。结果通过联合干预措施的有效落实,2013年住院患者抗菌药物使用率由1月份57.79%下降至12月份48.48%;医院感染率由2.07%下降至1.47%,例次感染率由2.58%下降至1.81%;漏报率由6.82%下降至2.63%;治疗使用抗菌药物病原学送检率由47.28%上升至55.25%。结论职能科室参与的多部门联合干预管理,是抗菌药物合理应用及医院感染控制的有效措施。
Objective To understand the effectiveness of antibacterials in combination intervention and provide the basis for further carrying out special rectification of clinical application of antibacterial drugs and nosocomial infection control. Methods A total of 26 686 hospitalized patients from January to December in 2013 from Department of Clinical Pharmacy and Hospital Infectious Diseases were tested for antibiotic use rate, nosocomial infection rate, Conduct surveys, compilation and analysis. Results The effective rate of antibacterials in inpatients decreased from 57.79% in January to 48.48% in December through effective implementation of joint interventions. The rate of nosocomial infections decreased from 2.07% to 1.47% and the rate of nosocomial infections decreased from 2.58% to 1.81 %; The false negative rate dropped from 6.82% to 2.63%; the rate of antimicrobial etiology used in the treatment increased from 47.28% to 55.25%. Conclusion The multi-department joint intervention management with functional departments is an effective measure to control the rational use of antimicrobial agents and control nosocomial infections.