论文部分内容阅读
目的比较新型甲型H1N1流感、季节性流感及普通上呼吸道感染的实验室检测特征,进一步认识新型甲型H1N1流感的特点并分析产生的可能机制。方法对我院2009年5～7月收治的新型甲型H1N1流感、季节性流感及普通上呼吸道感染病例的入院实验室检测资料进行回顾性分析。结果新型甲型H1N1流感患者入院时平均血钾为(3.43±0.33)mmol/L,低于季节性流感组和普通上呼吸道感染组,甲型H1N1流感中伴有低钾血症(血钾<3.5mmol/L)者占60.22%,明显高于另外两组,但合并低钾血症者的血钾平均值在三组间并无明显差异;与另两组相比,新型甲型H1N1流感组外周血白细胞、中性粒细胞、CD4+T细胞计数降低;其他实验室检测指标包括血钠、血钙、血磷、LDH活性、CK活性等在三组间并无统计学差异。结论新型甲型H1N1流感实验室检测特征包括血钾降低、白细胞、中性粒细胞、CD4+T细胞减少,其中低钾血症是新型甲型H1N1流感的一个显著实验室特征,其发生的具体机制尚待进一步研究。
Objective To compare the laboratory detection characteristics of new type A (H1N1), seasonal influenza and common upper respiratory tract infection and further understand the characteristics of the new type A (H1N1) influenza and analyze the possible mechanism. Methods A retrospective analysis was performed on laboratory laboratory data of new influenza A (H1N1), seasonal influenza and general upper respiratory tract infection admitted to our hospital from May to July in 2009. Results The average serum potassium level of new influenza A (H1N1) patients was (3.43 ± 0.33) mmol / L on admission, lower than that of seasonal influenza and common upper respiratory tract infection. Influenza A (H1N1) was associated with hypokalemia (serum potassium < 3.5 mmol / L) accounted for 60.22%, significantly higher than the other two groups, but the average serum potassium in patients with hypokalemia no significant difference between the three groups; compared with the other two groups, the new type A H1N1 influenza The counts of peripheral blood leukocytes, neutrophils and CD4 + T cells in the group were lower than those in the other groups. Other laboratory tests, including serum sodium, serum calcium, phosphorus, LDH activity and CK activity, were not statistically different among the three groups. Conclusion The laboratory features of the new influenza A (H1N1) virus include decreased serum potassium, decreased white blood cells, neutrophils and CD4 + T cells. Hypokalemia is a significant laboratory feature of the new type A (H1N1) flu and its occurrence is specific Mechanism needs further study.