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目的观察卡孕栓合用缩宫素预防产后出血的临床疗效。方法将我院2004年1月~2005年2月对350例正常足月阴道分娩的产妇随机分为两组。观察组:175例,于胎儿娩出后肌注缩宫素20U,并舌下含服卡孕栓1mg;对照组:175例,于胎儿娩出后单独肌注缩宫素20U。观察第三产程时间、产后2h阴道出血量及产后出血率。结果观察组第三产程时间为(7±3)m in,产后2h阴道出血量为(170±84)m l,产后出血率2.3%;对照组第三产程时间为(10±4)m in,产后2h阴道出血量为(257±98)m l,产后出血率7.4%,两组相比差异有统计学意义(P<0.01)。结论卡孕栓合用缩宫素促进宫缩,减少产后出血疗效满意,且使用方便、快速、安全。
Objective To observe the clinical efficacy of combination of oxytocin and prophylactic oxytocin in preventing postpartum hemorrhage. Methods From January 2004 to February 2005, 350 pregnant women with normal term vaginal delivery were randomly divided into two groups. The observation group: 175 cases, intrauterine injection of oxytocin 20U after intrauterine injection, and sublingual carbamazepine 1mg; control group: 175 cases, intramuscular injection of oxytocin alone after the baby was delivered 20U. Observation of the third stage of labor time, 2h postpartum vaginal bleeding and postpartum hemorrhage rate. Results The duration of the third stage of labor was (7 ± 3) min in the observation group, the amount of vaginal bleeding was (170 ± 84) ml at 2 h postpartum and the rate of postpartum hemorrhage was 2.3% in the observation group. The duration of the third stage of labor in the control group was (10 ± 4) Vaginal bleeding amount was (257 ± 98) ml and postpartum hemorrhage rate was 7.4% at 2h postpartum, the difference was statistically significant (P <0.01). Conclusions Combination of oxymatrine and oxytocin promotes uterine contractions and reduces postpartum hemorrhage with satisfactory results. It is convenient, rapid and safe to use.