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目的探讨早期干预对新生儿高胆红素血症患儿智能发育的影响。方法选取2004年1月至2005年12月在本院新生儿科住院的高胆红素血症患儿,除外颅内出血、先天愚型、先天畸型、代谢性疾病、耳疾患及耳毒性药物应用史,分为干预组及对照组。干预组出院后在医生的指导下由家属对患儿进行干预,并定期复查;对照组仅作定期复查。结果干预组和对照组患儿1岁时智能发育有明显差异,P<0.01。结论对新生儿高胆红素血症患儿进行早期干预可以促进神经系统发育,减少脑瘫的发生。
Objective To investigate the effect of early intervention on the intelligence development of neonates with hyperbilirubinaemia. Methods Children with hyperbilirubinemia who were hospitalized in neonatal department of our hospital from January 2004 to December 2005 were enrolled except for intracranial hemorrhage, Down’s syndrome, congenital malformations, metabolic diseases, ear diseases and ototoxic drugs , Divided into intervention group and control group. Intervention group after discharge under the guidance of a doctor intervention by the families of children, and regular review; control group only for regular review. Results There was a significant difference in intelligence development between the intervention group and the control group at 1 year of age (P <0.01). Conclusion Early intervention in neonates with hyperbilirubinaemia can promote nervous system development and reduce the occurrence of cerebral palsy.