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Objective: To investigate the apoptosis rules of the astrocytes and oligodendrocytes induced by Ca 2+ reperfusion. Methods: The apoptosis of purified cultured astrocytes and oligodendrocytes induced by Ca 2+ reperfusion and the relationship between the development of the cell apoptosis and post-reperfusion time was observed. Results: Both the astrocytes and oligodendrocytes were obviously in a time-dependent fashion, and the apoptosis ratios of the oligodendrocytes ( 39.73%± 4.16%) were higher than the astrocytes ( 19.64%± 4.67%) 24 hours after Ca 2+ reperfusion. The TUNEL positive cells were 13.6± 1.82 and 21.4± 1.95 at every visual field of astrocytes and oligodendrocytes respectively 24 hours after Ca 2+ reperfusion. Conclusions: The astrocytes and oligodendrocytes are similar with the development rules on apoptosis and have different susceptiveness to the situation.
Objective: To investigate the apoptosis rules of the astrocytes and oligodendrocytes induced by Ca 2+ reperfusion. Methods: The apoptosis of purified cultured astrocytes and oligodendrocytes induced by Ca 2+ reperfusion and the relationship between the development of the cell apoptosis and post-reperfusion time was observed. Both the astrocytes and oligodendrocytes were obviously in a time-dependent fashion, and the apoptosis ratios of the oligodendrocytes (39.73% ± 4.16%) were higher than the astrocytes (19.64% ± 4.67%) for 24 hours after Ca 2 + reperfusion. The TUNEL positive cells were 13.6 ± 1.82 and 21.4 ± 1.95 at every visual field of astrocytes and oligodendrocytes respectively 24 hours after Ca 2+ reperfusion. Conclusions: The astrocytes and oligodendrocytes are similar with the development rules on apoptosis and have different susceptiveness to the situation.