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糖尿病是一种常见的慢性代谢性疾病,已成为继恶性肿瘤和心脑血管疾病之后的第三大疾病。目前,对2型糖尿病发病机制尚不明确。近几十年来,研究表明肠道菌群与2型糖尿病的预防和治疗密切相关。益生菌及其补充剂预防2型糖尿病,是近年来随着人们对养生保健追求的逐渐提高才发展起来的一项新的研究课题,其价值受到许多微生物学家、营养学家、免疫学家高度重视。本研究综述了益生菌对2型糖尿病的潜在作用机制和研究方法进展,以期对以后精准医疗模式下防治2型糖尿病提供新的思路和靶点。
Diabetes is a common chronic metabolic disease that has become the third most common disease following malignancies and cardiovascular and cerebrovascular diseases. At present, the pathogenesis of type 2 diabetes is not yet clear. In recent decades, studies have shown that intestinal flora and type 2 diabetes prevention and treatment are closely related. Probiotics and supplements to prevent type 2 diabetes mellitus are new research topics that have been developed in recent years with the increasing pursuit of health care. The value of many biologists, nutritionists, immunologists highly valued. This review summarizes the potential mechanism of action of probiotics on type 2 diabetes mellitus and advances in research methods in order to provide new ideas and targets for the prevention and treatment of type 2 diabetes in the future.