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头颈部恶性肿瘤占全身癌肿的2%(原文如此),如属局灶者五年存活率为70%,有淋巴结转移者仅为30%。化学治疗:头颈癌对化疗有效果者为50~80%,对控制肿瘤作用有限,似乎不能抑制肿瘤生长,也不能抑制肿瘤转移,但术前采用化疗常可使肿瘤缩小,易确定肿瘤边缘;审慎的化疗可有效地缓解晚期头颈癌,但化疗的副作用仍难以避免。放射治疗:头颈癌放疗对多数小的限局性肿瘤常可获得与手术同等的效果。但颊沟处例外,此处手术治疗更好,因放疗后纤维化能使牙关活动受限。喉部肿瘤多选用放疗,对保存发音功能有益。放疗与手术可有几种结合方式,如根治性放疗后,仍有病灶残存或复发,可补以外科治疗。头颈部癌的放疗标准剂量为60~65Gy,分30~35次/6~7周。亦可为50~55Gy,分15次/3周。手术治疗前可有二种方式放疗;攻击性放疗(20Gy,分4次/周)或常规放疗(40Gy,分20次/4周)。后者便于观察肿瘤术前反应,如放疗效果
Head and neck malignancy accounts for 2% of all cancers in the body (original). In the case of a focal survivor, the five-year survival rate is 70%, and there is only 30% of lymph node metastases. Chemotherapy: Head and neck cancer is 50 to 80% effective for chemotherapy. It has limited effects on tumor control. It does not seem to inhibit tumor growth, nor does it inhibit tumor metastasis. However, chemotherapy can often shrink the tumor before surgery, and it is easy to determine the edge of the tumor. Prudent chemotherapy can effectively relieve advanced head and neck cancers, but the side effects of chemotherapy are still difficult to avoid. Radiotherapy: Radiotherapy for head and neck cancer can often achieve the same effect as surgery for most small, localized tumors. However, with the exception of the cheek groove, surgical treatment is better here, because fibrosis after radiotherapy can make the dental activity limited. The use of radiotherapy for the tumor of the larynx is beneficial to the preservation of the pronunciation function. Radiotherapy and surgery can have several combinations, such as radical radiotherapy, there are still residual or recurrence of the lesion, can be supplemented by surgical treatment. The standard dose of radiotherapy for head and neck cancer is 60 to 65 Gy, divided into 30 to 35 times/6 to 7 weeks. Can also be 50 ~ 55Gy, 15 times / 3 weeks. There are two modes of radiotherapy before surgery; aggressive radiation therapy (20 Gy, 4 times/week) or conventional radiotherapy (40 Gy, 20 times/4 weeks). The latter facilitates observation of preoperative tumor response, such as radiotherapy