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目的:比较中西医结合治疗与单纯西医治疗儿童特发性血小板减少性紫癜(ITP)的疗效。方法:采用Review Manager 4.2分析软件,对国内4篇有关中西医结合与单纯西医治疗儿童ITP疗效的研究结果进行随机效应模型的Meta分析。结果:中西医结合治疗组治疗ITP的痊愈率与总有效率均高于单纯西医治疗组,合并Z值分别为4.44和4.59,95%可信区间分别为(1.70,3.92)和(2.01,5.70)。结论:由于文献资料的局限,还不能完全肯定中西医结合治疗儿童ITP较单纯西医治疗儿童ITP更为有效,仍需大样本的、严格设计的随机双盲对照试验来进一步验证。
Objective: To compare the curative effect of traditional Chinese medicine and western medicine in treating idiopathic thrombocytopenic purpura (ITP) in children. Methods: Using Review Manager 4.2 analysis software, we conducted a meta-analysis of 4 randomized effect models of the results of 4 studies on ITP in children treated with Integrative Chinese and western medicine. Results: The cure rate and total effective rate of ITP in Integrative Medicine group were higher than that of Western medicine alone group, with a combined Z value of 4.44 and 4.59, 95% confidence intervals of (1.70, 3.92) and (2.01, 5.70 ). Conclusion: Due to the limitations of the literature, we can not fully confirm that ITP treatment of children with Chinese traditional and western medicine is more effective than western medicine alone. A large sample of strictly controlled double-blind randomized controlled trials is needed for further validation.