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目的 探讨地佐辛对单孔腹腔镜手术患者麻醉苏醒期恢复质量的影响.方法 择期静脉复合麻醉下行经脐单孔腹腔镜手术患者60例随机均分为两组,术毕前30 min静脉注射地佐辛0.1 mg/kg(A组)或等容量生理盐水(B组).记录麻醉前5min(T0)、拔管前5min(T1)、拔管后10 rin(T2)和拔管后30 min(T3)时的MAP和HR.记录患者T3、拔管后1 h(T4)和拔管后4 h(T5)时的躁动-镇静评分(RASS)和VAS疼痛评分.记录患者术后1d不良反应发生情况.结果 T1～T3时,A组的MAP和HR均低于B组(P＜0.05),B组MAP和HR高于T0时(P＜0.05).A组苏醒期RASS与VAS疼痛评分均优于B组(P＜0.05).A组苏醒期寒战发生率低于B组(P＜0.05).结论 术毕前静脉注射地佐辛能有效减轻经脐单孔腹腔镜手术患者术后疼痛,维持循环稳定,减少苏醒期不良反应.“,”Objective To observe the effect of dezocine on the quality of recovery from anesthesia in the patients underwent foramina singulare laparoscopic surgery.Methods Sixty patients undergoing transumbilical single-site laparoscopic surgery under intravenous general anesthesia were randomly divided into two groups with 30 cases each.The patients in group A were intravenously injected dezocine 0.1 mg/kg at 30 minutes before the end of surgery and those in group B were given normal saline as the controls.The MAP and HR were recorded at 5 min before anesthesia(T0),5 min before extubation (T1),10 min after extubation (T2) and 30 min after extubation (T3).The restless-sedation score (RASS) and VAS pain score were recorded at T3,1 h after extubation (T4)and 4 h after extubation (T5).The incidence of adverse events was recorded at 1 day after operation.Results During recovery from anesthesia,the MAP and HR were lower in group A than those in group B(P＜0.05),which in group B were higher during recovery period than those before anesthesia (P＜0.05).RASS and VAS pain score were better in group A than those in group B(P＜0.05).The incidence of shivering during recovery period was lower in group A than that in group B(P＜0.05).Conclusion Intravenous injection of dezocine before the end of surgery may effectively attenuate postoperative pain,maintain circulatory stability and reduce adverse effects during recovery from anesthesia in the patients underwent foramina singulare laparoscopic surgery.